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Herefordshire & Worcestershire
Medicines and Prescribing Committee
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 Formulary Chapter 4: Central nervous system - Full Chapter
04.02.01  Expand sub section  Antipsychotic Drugs
 note  Other antipsychotic drugs may be available at the request of Consultant Psychiatrist
04.02.01  Expand sub section  Atypical Antipsychotics
Amisulpride
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Amber

In Line With NICE CG178 (Replaces TA43)

 
Link  NICE CG178 - Psychosis and schizophrenia in adults: prevention and management
 
Aripiprazole Oral
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Amber

In Line With NICE TA213
Schizophrenia in people aged 15 to 17 years who are intolerant of resperidone, or for who risperidone is contraindicated, or whose schizophrenia has not been adequately controlled with risperidone

In Line With Nice TA292
Aripiprazole as a possible treatment (for up to 12 weeks) for moderate to severe manic episodes in young people aged 13 and older with bipolar I disorder.

 
Link  NICE TA213: Schizophrenia - aripiprazole
Link  NICE TA292 - Aged 13 and older with bipolar I disorder.
 
Clozapine
View adult BNF View SPC online View childrens BNF 		Restricted Drug Restricted
Red

Consultant Psychiatrist initiation / secondary care prescribing only. Not for prescribing in primary care.

 
Link  Drug Safety Update (Aug 20): Clozapine and other antipsychotics: monitoring blood concentrations for toxicity
 
Olanzapine Tablets and orodispersible tablets
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Amber

In Line With NICE CG185 and CG178 (Replaces TA43).


Oral lyophilisates sugar free tablets are not included in the formulary as they are  substantially more expensive.

 
Link  NICE CG178 - Psychosis and schizophrenia in adults: prevention and management
Link  NICE CG185 - Bipolar disorder: assessment and management
 
Quetiapine
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Amber

In Line With NICE CG178 (Replaces TA43)

 
Link  NICE CG178 - Psychosis and schizophrenia in adults: prevention and management
 
Quetiapine Modified Release
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Amber

In Line With NICE CG178 (Replaces TA43)

If a modified release preparation is required, then preferred brands are:

      • Sondate® XL (1st line choice)
      • Mintreleq® XL
      • Biquelle® XL

 
Link  NICE CG178 - Psychosis and schizophrenia in adults: prevention and management
 
Risperidone
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Amber

In Line With NICE CG178 (Replaces TA43)

 
Link  NICE CG178 - Psychosis and schizophrenia in adults: prevention and management
 
Olanzapine Long Acting Injection (Zypadhera®)
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Red 		 
Link  NICE CG178 - Psychosis and schizophrenia in adults: prevention and management
 
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
 Display tracking information
click to search medicines.org.uk
 Link to adult BNF
click to search medicines.org.uk
 Link to children's BNF
click to search medicines.org.uk
 Link to SPCs
Cytotoxic Drug
 Cytotoxic Drug
CD
 Controlled Drug
High Cost Medicine
 High Cost Medicine
Cancer Drugs Fund
 Cancer Drugs Fund
NHSE
 NHS England
Homecare
 Homecare
CCG
 CCG

Traffic Light Status Information

Status Description

Red

 Secondary care only, not to be prescribed in primary care.   

Amber 2

 Specialist initiation with shared care guidance Medicines which should be initiated in secondary care by the specialist with follow-on prescription and monitoring according to a specific Shared Care (SC) Guideline. Prescribing may be continued in primary care in line with a shared care guideline   

Amber with Shared Care

 Specialist initiation with shared care guidance Medicines which should be initiated in secondary care by the specialist with follow-on prescription and monitoring according to a specific Shared Care (SC) Guideline. Prescribing may be continued in primary care in line with a shared care guideline   

Amber

 Considered suitable for primary care prescribing following specialist initiation/recommendation.  

Green

 Considered appropriate for prescribing in both secondary and primary care. Suitable for initiation in primary care.   

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