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Herefordshire & Worcestershire
Medicines and Prescribing Committee
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 Formulary Chapter 4: Central nervous system - Full Chapter
04.09.01  Expand sub section  Dopaminergic drugs used in Parkinsons disease
04.09.01  Expand sub section  Dopamine receptor agonists
Apomorphine Hydrochloride (APO-go)
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Formulary
Amber with Shared Care

Consultant initiation only - may be continued by GP in line with Shared Care Guideline

 
Link  Herefordshire Apomorphine Shared Care
Link  MHRA Drug Safety Update (April 2016): Apomorphine with domperidone: minimising risk of cardiac side effects
 
Bromocriptine
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Formulary
Amber

Specialist initiation only 


Note: Ergot-derived dopamine receptor agonists have been associated with pulmonary, retroperitoneal and pericardial fibrotic reactions. 

 
 
Cabergoline
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Formulary
Amber

Specialist initiation only 


Note: Ergot-derived dopamine receptor agonists have been associated with pulmonary, retroperitoneal and pericardial fibrotic reactions.

 
 
Pergolide
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Formulary
Amber

Specialist initiation only 


Note: Ergot-derived dopamine receptor agonists have been associated with pulmonary, retroperitoneal and pericardial fibrotic reactions. 

 
 
Pramipexole
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Formulary
Amber

Specialist initiation only

Preferred modified release brand is Pipexus®
 

 
 
Ropinirole
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Formulary
Amber

Specialist initiation only
 

 
 
Rotigotine
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Formulary
Amber

In PD specialist initiation 
 
In Restless Leg Syndrome consultant recommendation only in patients with severe RLS where treatment with pramipexole and ropinirole has failed.

 
 
04.09.01  Expand sub section  Levodopa
04.09.01  Expand sub section  Monoamine-oxidase-B inhibitors
04.09.01  Expand sub section  Catachol-O-methyltransferase inhibitors to top
04.09.01  Expand sub section  Amantadine
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Secondary care only, not to be prescribed in primary care.   

Amber 2

Specialist initiation with shared care guidance Medicines which should be initiated in secondary care by the specialist with follow-on prescription and monitoring according to a specific Shared Care (SC) Guideline. Prescribing may be continued in primary care in line with a shared care guideline   

Amber with Shared Care

Specialist initiation with shared care guidance Medicines which should be initiated in secondary care by the specialist with follow-on prescription and monitoring according to a specific Shared Care (SC) Guideline. Prescribing may be continued in primary care in line with a shared care guideline   

Amber

Considered suitable for primary care prescribing following specialist initiation/recommendation.  

Green

Considered appropriate for prescribing in both secondary and primary care. Suitable for initiation in primary care.   

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